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Novel Pharmacological Inhibitors for Bacterial Protein ToxinsVerfasser: Barth, Holger Verlag: MDPI - Multidisciplinary Digital Publishing Institute Jahr: 2017 Umfangsangabe: 1 electronic resource (VI, 118 p.) Grundsignatur: eBook » E-Book
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Grundsignatur: eBook
Verfasser:
Titel: Novel Pharmacological Inhibitors for Bacterial Protein Toxins
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URL:
Verlag: MDPI - Multidisciplinary Digital Publishing Institute
ISBN (falsch): 9783038424314
ISBN (falsch): 9783038424307
Jahr (Ansetzg): 2017
Jahr: 2017
Umfangsangabe: 1 electronic resource (VI, 118 p.)
Schrift/Sprache: English
Schlagwort 710: Toxicology. Poisons
Schlagwort 710: Biology (General)
Abstract: Many medically relevant bacteria cause severe human and animal diseases because they produce and release protein toxins that target mammalian cells. Because the toxin-induced cell damage is the reason for the clinical symptoms, the targeted pharmacological inhibition of the cytotoxic mode of action of bacterial toxins should prevent or cure the respective toxin-associated disease. Toxin inhibitors might be beneficial when the toxin acts in the absence of the producing bacteria (e.g., food poisoning), but also in combination with antibiotics in infectious diseases when the toxin-producing bacteria are present. The focus of this Special Issue of Toxins is on the development and characterization of novel inhibitors against bacterial toxins, e.g., toxin neutralizing antibodies, peptides or small compounds, as well as toxin pore blockers, which interfere with bacterial toxins and thereby protect cells from intoxication
Lokal-ISN: HL012625468
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